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GFLIP
02-02-2007, 08:11 PM
Which of the following promote humoral immunity?

a. IL-1
b. IL-5
c. IL-12
d. IL-18
e. IL-22
f. IFN gamma

Hatim
02-02-2007, 08:47 PM
umm this is a striaght up guess i need to dust up my immuno but i'm thinking IL-5?

lmoliver
02-03-2007, 06:24 AM
Which of the following promote humoral immunity?

a. IL-1
b. IL-5
c. IL-12
d. IL-18
e. IL-22
f. IFN gamma

A list of interleukins with function:

IL-1: secreted by macrophages, induces acute phase reaction
IL-2: secreted by T cells in an autocrine fashion, stimulates growth and differentiation of T cell response. Can be used in immunotherapy to treat cancer.
IL-3: secreted by T cells, stimulates bone marrow stem cells.
IL-4: involved in proliferation of B cells and the development of T cells and mast cells. Important role in allergic responses.
IL-5: role in differentiation of B cells, eosinophil production, and IgA production
IL-6: secreted by macrophages, induces acute phase reaction
IL-7: involved in B, T, and NK cell survival, development, and homeostasis
IL-8: Neutrophil chemotaxis
IL-9: stimulates mast cells
IL-10: inhibits Th1 cytokine production
IL-11: acute phase protein production
IL-12: NK cell stimulation, Th1 cells induction
IL-13: Stimulates growth and differentiation of B-Cells, inhibits Th1 cells and the production of macrophage inflammatory cytokines
IL-15: Induces production of Natural Killer Cells
IL-17: Induces production of inflammatory cytokines
IL-18: Induces production of Interferon-Gamma (IFNy)
IL-23: Increases angiogenesis but reduces CD8 T-cell infiltration
Straight forward you say. I think the question is a bit confusing. By humoral immunity are you talking about antibodies? Thanks for the question.

lmoliver
02-03-2007, 06:24 AM
Which of the following promote humoral immunity?

a. IL-1
b. IL-5
c. IL-12
d. IL-18
e. IL-22
f. IFN gamma

A list of interleukins with function:

IL-1: secreted by macrophages, induces acute phase reaction
IL-2: secreted by T cells in an autocrine fashion, stimulates growth and differentiation of T cell response. Can be used in immunotherapy to treat cancer.
IL-3: secreted by T cells, stimulates bone marrow stem cells.
IL-4: involved in proliferation of B cells and the development of T cells and mast cells. Important role in allergic responses.
IL-5: role in differentiation of B cells, eosinophil production, and IgA production
IL-6: secreted by macrophages, induces acute phase reaction
IL-7: involved in B, T, and NK cell survival, development, and homeostasis
IL-8: Neutrophil chemotaxis
IL-9: stimulates mast cells
IL-10: inhibits Th1 cytokine production
IL-11: acute phase protein production
IL-12: NK cell stimulation, Th1 cells induction
IL-13: Stimulates growth and differentiation of B-Cells, inhibits Th1 cells and the production of macrophage inflammatory cytokines
IL-15: Induces production of Natural Killer Cells
IL-17: Induces production of inflammatory cytokines
IL-18: Induces production of Interferon-Gamma (IFNy)
IL-23: Increases angiogenesis but reduces CD8 T-cell infiltrationStraight forward you say. I think the question is a bit confusing. By humoral immunity are you talking about antibodies? Thanks for the question.

preetin
02-03-2007, 02:39 PM
answer is IL-5

IL-2,4,5,6 help in humoral immunity.

GFLIP
02-03-2007, 03:24 PM
Straight forward you say. I think the question is a bit confusing. By humoral immunity are you talking about antibodies? Thanks for the question.

umm... dude... it was straight forward... i didn't list all those IL's ;)
... and humoral immunity is Ab's ...

btw. IL-5 is correct.