Hiv Q

[GFLIP]

The CDC estimates that about 40,000 people in the US become infected with HIV each year. Advances in treatment have slowed the progression of HIV to AIDS. It has also led to decreased deaths in AIDS patients. Aside from medical advances, genetics also plays a role in slowing the progression of the disease. Which of the following genes slows the progression of the disease?

a. pol
b. tat
c. rev
d. ltr
e. vif
f. nef
g. vpu
h. tor

[preetin]

well Im not sure but is it tat gene...?

[lmoliver]

The CDC estimates that about 40,000 people in the US become infected with HIV each year. Advances in treatment have slowed the progression of HIV to AIDS. It has also led to decreased deaths in AIDS patients. Aside from medical advances, genetics also plays a role in slowing the progression of the disease. Which of the following genes slows the progression of the disease?

a. pol
b. tat
c. rev
d. ltr
e. vif
f. nef
g. vpu
h. tor

"The GAG gene and the GAG and POL genes together are translated into large polyproteins which are then cleaved by a virus-encoded protease that is part of the POL polyprotein. " I found this on my virology website. I think it's "protease inhibiors." and I would say the answer is

a. pol

[preetin]

so what is the corrent answer?

[GFLIP]

the pol gene encodes for viral enzymes (needed by the virus).

the answer is nef gene

[preetin]

but in kaplan it said...initially thought to downregulate HIV production; now thought to enhance the pathogenicity of HIV

[GFLIP]

nef stands for negative regulatory factor... if you have it, you have a negative effect on AIDS.

tat is the opposite. it speeds up the progression of AIDS.

[preetin]

okay thanks ...i get it