tommyk
10-05-2006, 04:40 PM
Hy 2429 A GOLDEN High Yielder… Know the answer choices cold on this one!
A 30-year-old man who recently came from Italy returns to you for a follow up visit to evaluate his anemia. Four days ago, he presented with fatigue and dyspnea on exertion, and was found to have a hematocrit of 20%. You admit him to your home hospital basement. Laboratory analysis shows:
Hematocrit........................................ 20%
Mean corpuscular volume (MCV)......60 µm3
Reticulocyte count.............................4.0%
Serum iron........................................160 µg/dL
Total iron binding capacity (TIBC).....250 µg/mL
Serum ferritin………………………….80
Electrophoresis shows no alpha bands:
What is this ULTRA High Yield disease? KNOW EVERY SINGLE one of the following. Ignore them at your own peril…
a) Sideroblastic anemia
b) Iron def. Anemia
c) Multiple Myeloma
d) Alpha thalassemia
e) Beta thalassemia
f) Megaloblastic anemia
g) Anemia of Chronic disease
ans) pick choice E. This is a patient of Mediterranean descent who has a microcytic anemia with an appropriate reticulocyte count, normal iron studies and a hemoglobin electrophoresis with an increased alpha chain component of hemoglobin. The thalassemias are a heterogeneous group of inherited disorders characterized by the underproduction of either the alpha or the beta chains of the hemoglobin molecule. In beta thalassemia, a reduced production of beta chains occurs with normal amounts of alpha production. Iron deficiency anemia although a microcytic anemia, is not supported by the normal iron studies. Megaloblastic anemia is not supported by the low MCV.
A 30-year-old man who recently came from Italy returns to you for a follow up visit to evaluate his anemia. Four days ago, he presented with fatigue and dyspnea on exertion, and was found to have a hematocrit of 20%. You admit him to your home hospital basement. Laboratory analysis shows:
Hematocrit........................................ 20%
Mean corpuscular volume (MCV)......60 µm3
Reticulocyte count.............................4.0%
Serum iron........................................160 µg/dL
Total iron binding capacity (TIBC).....250 µg/mL
Serum ferritin………………………….80
Electrophoresis shows no alpha bands:
What is this ULTRA High Yield disease? KNOW EVERY SINGLE one of the following. Ignore them at your own peril…
a) Sideroblastic anemia
b) Iron def. Anemia
c) Multiple Myeloma
d) Alpha thalassemia
e) Beta thalassemia
f) Megaloblastic anemia
g) Anemia of Chronic disease
ans) pick choice E. This is a patient of Mediterranean descent who has a microcytic anemia with an appropriate reticulocyte count, normal iron studies and a hemoglobin electrophoresis with an increased alpha chain component of hemoglobin. The thalassemias are a heterogeneous group of inherited disorders characterized by the underproduction of either the alpha or the beta chains of the hemoglobin molecule. In beta thalassemia, a reduced production of beta chains occurs with normal amounts of alpha production. Iron deficiency anemia although a microcytic anemia, is not supported by the normal iron studies. Megaloblastic anemia is not supported by the low MCV.