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Unregistered101
10-04-2006, 09:46 AM
A 70 year old patient presents with fatigue, night sweats, generalized lymphadenopathy, hepatosplenomegaly. In addition, his examination reveals an anemia with thrombocytopenia and neutropenia. A peripheral smear shows numerous small lymphocytes, some of which appear to have been disrupted during the process of making the smear. Identify the marker or markers present on the abnormal cells that could be used for its identitu in a flow cytometric analyzer?

a) CD 8

b) CD 3

c) CD14

D) CD 19 AND CD 20

E) CD 16 AND CD 56

Follow up question: In this condition, you see on a small minority of normal B cells an "atypical" marker. Name it?

roxanac24
10-04-2006, 10:00 AM
I think the answer is (D) CD 19 and CD 20 - the pan B-cell markers.
Could the "atypical" marker be CD5 (T-cell marker)?

Unregistered101
10-04-2006, 10:10 AM
What does this pt have then? Good job! You got....