tommyk
10-03-2006, 11:58 AM
Hy 2406 Pharm…This drug…came up…
q) A 70-year-old woman named Michelle Rodriguez initiates chemotherapy for metastatic breast cancer. She develops severe nausea during her chemotherapy. Which of the following would be most effective in controlling her vomiting if given these choices? A secondary: What is the mech of action of the said drug?
a-Morphine
b-Bismuth, Pepto…you know
c-Ondansetron
d-Drano
e-Heroin
a) This is a classic Step 1 drug. Pick c, Ondansetron to control the vomiting and nausea. This drug is a selective inhibitor of one type of the 5-hydroxytryptamine (synonym serotonin) receptor, which is present both peripherally on vagal nerves and centrally in the chemoreceptor trigger zone of the area postrema of the brain. Bismuth helps w/ nausea and vomiting, but NOT w/ that assoc. w/ chemo.
q) A 70-year-old woman named Michelle Rodriguez initiates chemotherapy for metastatic breast cancer. She develops severe nausea during her chemotherapy. Which of the following would be most effective in controlling her vomiting if given these choices? A secondary: What is the mech of action of the said drug?
a-Morphine
b-Bismuth, Pepto…you know
c-Ondansetron
d-Drano
e-Heroin
a) This is a classic Step 1 drug. Pick c, Ondansetron to control the vomiting and nausea. This drug is a selective inhibitor of one type of the 5-hydroxytryptamine (synonym serotonin) receptor, which is present both peripherally on vagal nerves and centrally in the chemoreceptor trigger zone of the area postrema of the brain. Bismuth helps w/ nausea and vomiting, but NOT w/ that assoc. w/ chemo.