Physiology question

[dr41]

Can any one explain to me how hyperprolactinemia causes amenorrhea?:confused:

[IMG SURVIVOR]

Remember that prolactin will inhibit the release of GnRH and as conclucion you will not have OVULATION


Allways remember that if you have a baby and you are breatfiding you DONT want another baby

[dr41]

Oops! Y couldn't I think of it? Thanx IMG SURVIVOR!!!!!!

[IMG SURVIVOR]

no problem that is the reason of this forum

[Scott Kahn MD]

Exactly. High levels of prolactin inhibit the pulsatile release of GnRH. No GnRH, no ovulation.

[elektra]

Remember that as prolactin inhibit the release of the gonadotropin releaising hormone (GNRH) in women it dose the same thing on men....so what´s the effect of this inhibition on men?









Decrease in the release of GnRH cause a decrease of FSH acting on Sertoli cells wich normally maintains spermatogenesis, the net effect is a inhibition of spermatogenesis
:shock:

[IMG SURVIVOR]

And what medication can you give to a patient with hyperprolactinemia that you can also use for PARKINSONS?







Bromociptine

[elektra]

Yes bromocriptine wich is a dopamine partial agonist acting on the tubero-infundibular dopaminergic pathway. The release of DA cause the release of PIF hypothalamus wich cause a inhibition of the release of prolactin on anterior pituitary.




Can U name another DA agonist?





Pergolide :D

This is good stuff!!!!