Quote:
Originally Posted by wcb22
yes it makes more malate, but only oxaloacetate can go up to phosphoenolpyruvate in gluconeogenesis. malate cannot do it.
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Isnt malate from mitochondria will use the malate shuttle to go out to cytoplasm, then convert to OAA? So if you have an accumlation of Malate in the mitochondria why wouldnt you have extra malate on the outside via the shuttle, and then why wouldnt it be convert to OAA. That is what i confuse on.