in my opinion, i would say its difficult to say when theres an acidosis, there will be such and such.. and if its alkalosis, there will be such and such. its important know why there is an acidosis to begin with and that could explain the hypo/hyper kalemia situations as both are possible. The generalization of saying in acidosis, there will be hyperkalemia is only a generalization. lol.. not much of wisdom there.

Whenever you see the word acidosis/alkalosis in a same context of "Chronic" i would always always always think.. "compensation" (probably opposite). Our body really does wonders.

1) just few thoughts: if theres lack of aldosterone - less sodium, more K+, more H+ (acidosis and hyperkalemia). Hyperkalemia to begin with can inhibit H+ excretion hence acidosis. For chronic, remember K+ is capable of absorbing or excreting 1-100% of dietary K in the DCT/CT.. when there's a need, it does its job.

2) chronic - K+ shift compensated.

3) when we measure K+.. we detect it by measuring it off the ECF. The driving force for excretion or reaborption actually relies on the metabolic changes in ICF. so the general idea is that when there is an alkalosis - H+ goes out, K+ comes in. The cell thinks it got lots of K+ inside the cell so time to increase K+ excretion.

To get you thinking.. apply the third concept that i said to your 1 question now.. and it should definitely help. Hope i didnt complicate it.

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